This list contains the Partitioned Survival Model (PSM) parameters including various cost, probability, and utility values used in the model.
Format
A list with the following components:
- body_weight
Body weight in kilograms, 15.
- GD2_unit_mg
Unit dose of Dinutuximab β (GD2) in milligrams, 20.
- GD2_dose_days
Number of days on Dinutuximab β per cycle, 5.
- GD2_unit_price
Unit price of Dinutuximab β, 8790.26.
- TT_unit_mg
Unit dose of Isotretinoin (TT) in milligrams, 10.
- TT_dose_days
Number of days for Isotretinoin dosing, 14.
- TT_unit_price
Unit price of Isotretinoin, 0.24.
- GD2_aEvents_names
Names of adverse events for GD2:
- fever
Fever
- diarrhea
Diarrhea
- vomiting
Vomiting
- infection
Infection
- hypersensitivity_reaction
Hypersensitivity reaction
- capillary_leak
Capillary leak
- prob_fever
Probability of fever, 0.18.
- prob_diarrhea
Probability of diarrhea, 0.07.
- prob_vomiting
Probability of vomiting, 0.06.
- prob_infection
Probability of infection, 0.21.
- prob_hypersensitivity_reaction
Probability of hypersensitivity reaction, 0.11.
- prob_capillary_leak
Probability of capillary leak, 0.06.
- cost_fever
Cost of fever, 1.98.
- cost_diarrhea
Cost of diarrhea, 3.2.
- cost_vomiting
Cost of vomiting, 8.45.
- cost_infection
Cost of infection, 222.33.
- cost_hypersensitivity_reaction
Cost of hypersensitivity reaction, 4.13.
- cost_capillary_leak
Cost of capillary leak, 307.37.
- cost_pain
Cost of pain, 6.36.
- cost_laboratory
Cost of laboratory services, 141.45.
- cost_hospitalisation
Cost of hospitalisation, 3763.62.
- Temo_unit_mg
Unit dose of Temozolomide (Temo) in milligrams, 50.
- Temo_dose_days
Number of days on Temozolomide per cycle, 5.
- Temo_unit_price
Unit price of Temozolomide, 15.34.
- Iri_unit_mg
Unit dose of Irinotecan (Iri) in milligrams, 40.
- Iri_dose_days
Number of days on Irinotecan per cycle, 5.
- Iri_unit_price
Unit price of Irinotecan, 4.4.
- u_EFS
Utility value for Event-Free Survival (EFS), 0.84.
- u_PPS
Utility value for Post-Progression Survival (PPS), 0.56.